Steven Gerrard’s side will face each of the three teams once, either home or away, with the winner of the section progressing to the tournament’s quarter-finals.
The two best runners-up in the six overall groups will also claim a place in the last eight, with the format then becoming a knockout system in one-off ties.
Gerrard’s charges drew 1-1 at Derby County in their opening U18 Premier League match of the season on Friday afternoon.