Daniel Sturridge and Georginio Wijnaldum have come into Liverpool's starting XI, with Philippe Coutinho and Emre Can dropping out.
Klopp revelaed in Friday's press conference that Coutinho was facing a battle to be fit due to an adductor injury and the Brazilian is not included in the Reds' matchday squad. Can, meanwhile, is on the bench.
"Phil is out today so it was clear that we had to make a change and that's what we did," the boss said, explaining Sturridge's inclusion during his pre-match media duties.
"Gini is back and trained completely normal so it was then clear that we wanted to have him on the pitch."
On whether he is expecting a strong reaction from his side following last week's defeat to Tottenham Hotspur, the manager continued: "If training is the decisive sign then everything is absolutely in the right direction, the boys did really well in training, they were really focused and all that stuff but that's normal.
"To be honest they're always like this, we never had problems in training so far, but of course we have to show a reaction, that's how it is. We have to show Huddersfield this is Anfield, this is our home and nothing else.
"Of course I read after the Huddersfield v United game that United were surprised by the intensity, stuff like this, so we will not be surprised about the intensity, we need to be there from the first second, that's clear.
"Of course you can imagine everyone spoke about our defending in the last week and we did the same, but in another way I would say.
"As I said before, we have to show a reaction, we have to defend better and we have to still play football because we need to create chances."