The Reds are back in action 48 hours on from their 2-1 home victory against Leicester City, prompting the manager to shuffle his options.
Adam Lallana makes his first start of 2017-18, while Simon Mignolet returns in goal and captains the side.
Philippe Coutinho and Mohamed Salah miss out with respective minor thigh and groin injuries.
Liverpool team: Mignolet, Alexander-Arnold, Klavan, Lovren, Gomez, Can, Wijnaldum, Lallana, Oxlade-Chamberlain, Mane, Solanke.
Substitutes: Karius, Milner, Firmino, Robertson, Ings, Matip, Woodburn.