The captain is restored to midfield with Georginio Wijnaldum, while Joe Gomez and Joel Matip return in defence.
It’s Henderson’s 200th league appearance for the Reds.
Elsewhere, Dejan Lovren misses out due to a minor ankle issue, while Adam Lallana is not part of the matchday squad as he continues to work his way back to full match fitness.
Liverpool: Karius, Gomez, Matip, Van Dijk, Robertson, Henderson, Wijnaldum, Can, Mane, Salah, Firmino.
Subs: Mignolet, Milner, Klavan, Moreno, Oxlade-Chamberlain, Ings, Alexander-Arnold.