The forward was left out of the matchday squad for Saturday's Merseyside derby meeting with Everton at Goodison Park after sustaining a groin injury in the first leg of the quarter-final tie with Pep Guardiola's side in midweek.
However, Klopp is optimistic on his chances of being ready for the return meeting - as well as those of Andy Robertson, who missed the encounter with the Blues due to a calf issue.
The manager said: "Mo, he's injured. I don't think it is really serious and he can be available for Tuesday but for today he wasn't available. It's the same with Robbo."