After seven-year spells with both FSV Mainz and Borussia Dortmund, the German took on a new challenge in the Premier League with the Reds.
Klopp was officially confirmed as the club's new boss on October 8, 2015 and took charge of his first game nine days later.
Three years and 166 matches on, he has taken his side to three major finals and made an unbeaten start to the new league campaign.
For a range of facts and figures from Klopp's three years as Reds boss, courtesy of official LFC statistician Ged Rea, read on...
333 – goals scored in league and cup. Emre Can netted the first in the home game with Rubin Kazan
219 – points won by Klopp in the Premier League, from 114 matches at an average of 1.92 per game
166 – games played in the Klopp era in all competitions
148 – Roberto Firmino has made the most appearances for the club since Jürgen took charge
76 – the quickest goal in seconds scored by a Liverpool player from the start of a game (Daniel Sturridge against Newcastle United in April 2016)
63 – clean sheets kept by Liverpool in all competitions since Klopp was appointed, the first coming against Tottenham Hotspur in October 2015
58 – players have been used by the club in the last 166 games
53 – the percentage of wins overseen by Klopp in his opening three years at the helm (88 wins in 166 games)
53 – the tally of goals scored by Liverpool's highest scorer: Firmino
52 – cup ties have been played by Liverpool (17 Champions League, 13 Europa League, 13 League Cup, nine FA Cup)
45 – the average number of minutes between Liverpool goals (333 goals in 14,940 minutes)
45 – different teams Klopp has faced as Reds boss - 40 of those have been beaten
36 – the number of times the most used centre-back pairing has been deployed, with Dejan Lovren and Joel Matip on the losing team only four times
34 – the number of different Liverpool players to have scored under Klopp
34 – goals scored by Liverpool substitutes - with the most coming from Sturridge (eight)
29 – players have been given their Reds debut, with Fabinho, against Paris Saint-Germain, the most recent
29 – the number of occasions the Reds have scored four goals or more in a game
21 – the average age of the youngest starting XI fielded by Klopp and, indeed, ever by Liverpool - against Plymouth Argyle in the FA Cup in January 2017 (21 years and 296 days)
18 – the longest unbeaten run, from October 2017 to January 2018 (18 games)
14 – the Reds have come from behind to win a game on 14 occasions under Klopp
13 – the number of different players to captain the team - James Milner, Kolo Toure, Lucas Leiva, Jordan Henderson, Christian Benteke, Joe Allen, Jose Enrique, Jon Flanagan, Martin Skrtel, Can, Philippe Coutinho, Simon Mignolet, Lovren
10 – Liverpool are unbeaten against 10 teams in the Premier League under Klopp
6 – players remain at Anfield who started Klopp's first game at Tottenham in October 2015