The Netherlands midfielder replaces Adam Lallana in the Reds’ starting XI in the only alteration to the team deployed at West Ham United on Monday night.
Trent Alexander-Arnold and Jordan Henderson return on the bench following injuries, but Xherdan Shaqiri misses out due to a slight abdominal strain.
Liverpool: Alisson, Milner, Matip, Van Dijk, Robertson, Wijnaldum, Fabinho, Keita, Mane, Salah, Firmino.
Subs: Mignolet, Henderson, Sturridge, Lallana, Origi, Camacho, Alexander-Arnold.