Liverpool host the Bundesliga side at Anfield in the first leg of their last-16 clash on Tuesday night.
A return from a hamstring injury remains a possibility for Lovren, while the Reds will assess Shaqiri in the final hours before the game.
Wijnaldum has been back in training after a bout of illness.
Asked for the latest team news on Monday morning, Klopp told Liverpoolfc.com: “I don’t know 100 per cent. It’s Monday and we play on Tuesday so most of that should be clear.
“Gini trained and looked really well. Shaq did a lot, so it will be close, we have to see.
“Dejan, I actually have to wait minute by minute if there is a chance or not.
“But that’s pretty much all, I would say.”