The forward replaces the injured Roberto Firmino in attack for the Premier League encounter.
Elsewhere, Trent Alexander-Arnold comes in for Jordan Henderson in the only other alteration made by Jürgen Klopp to the team deployed at Manchester United on Sunday.
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson, Fabinho, Wijnaldum, Milner, Mane, Salah, Origi.
Subs: Mignolet, Keita, Henderson, Sturridge, Lallana, Shaqiri, Camacho.