The pair are two of five changes made by Jürgen Klopp for the encounter at Besiktas Park, joining Mohamed Salah in attack.
Elsewhere, Adrian replaces the injured Alisson Becker in goal, while Joel Matip and James Milner come into the line-up.
Naby Keita is ruled out with a muscle strain.
Liverpool: Adrian, Gomez, Matip, Van Dijk, Robertson, Fabinho, Milner, Henderson, Oxlade-Chamberlain, Mane, Salah.
Subs: Lonergan, Kelleher, Wijnaldum, Firmino, Lallana, Shaqiri, Brewster, Origi, Hoever, Alexander-Arnold, Elliott.