The champions will begin the defence of their title with a home match against Championship winners Leeds United.
Jürgen Klopp's Reds are then set to travel to Chelsea, before hosting Arsenal at Anfield as the season gets under way.
Merseyside derbies are pencilled in for October 17 (Goodison Park) and February 20 (Anfield).
Liverpool face Manchester United on January 16 (home) and May 1 (away), and take on Manchester City on November 7 (away) and February 6 (home).
They conclude the season with a home match against Crystal Palace on Sunday May 23.
See the Reds' full Premier League fixture list for 2020-21 below.
All fixtures are subject to change, with broadcast selections to follow in due course.
2020-21 Premier League fixture list
September
12 – Leeds United (H)
19 – Chelsea (A)
26 – Arsenal (H)
October
3 – Aston Villa (A)
17 – Everton (A)
24 – Sheffield United (H)
31 – West Ham United (H)
November
7 – Manchester City (A)
21 – Leicester City (H)
28 – Brighton & Hove Albion (A)
December
5 – Wolverhampton Wanderers (H)
12 – Fulham (A)
16 – Tottenham Hotspur (H)
19 – Crystal Palace (A)
26 – West Bromwich Albion (H)
28 – Newcastle United (A)
January
2 – Southampton (A)
13 – Burnley (H)
16 – Manchester United (H)
27 – Tottenham Hotspur (A)
30 – West Ham United (A)
February
3 – Brighton & Hove Albion (H)
6 – Manchester City (H)
13 – Leicester City (A)
20 – Everton (H)
27 – Sheffield United (A)
March
6 – Fulham (H)
13 – Wolverhampton Wanderers (A)
20 – Chelsea (H)
April
3 – Arsenal (A)
10 – Aston Villa (H)
17 – Leeds United (A)
24 – Newcastle United (H)
May
1 – Manchester United (A)
8 – Southampton (H)
11 – West Bromwich Albion (A)
15 – Burnley (A)
23 – Crystal Palace (H)