The defender will make his first ever top-flight appearance for the Reds alongside Joe Gomez in the absence of Virgil van Dijk, Joel Matip and Fabinho.
Elsewhere, Curtis Jones begins in midfield.
Liverpool: Alisson, Alexander-Arnold, Phillips, Gomez, Robertson, Henderson, Wijnaldum, Jones, Mane, Salah, Firmino.
Subs: Adrian, Milner, Minamino, Jota, Shaqiri, R. Williams, N. Williams.