The Reds have taken down AFC Ajax and FC Midtjylland so far in Group D and could make it nine points from a possible nine in Italy tonight.
Earning three points would represent a fourth successive group-stage away victory for Jürgen Klopp's side – following the wins at Genk and Salzburg last season and last month’s success at Ajax.
For more pre-match facts and figures, courtesy of LFC statistician Ged Rea, read on...
Atalanta will be Liverpool's 132nd different European opponent.
Mohamed Salah is the club's third-highest scorer in Europe – only Steven Gerrard (41) and Michael Owen (22) have scored more. The Egyptian's 21 goals in the Champions League for the Reds have come in just 37 appearances.
Salah is off to his best scoring start to a season. He has eight goals in 11 games. In his previous seasons it has taken him 13, 17 and 14 games to reach eight goals.
Diogo Jota could become the first player since Sadio Mane in February 2019 to score in a fourth successive Liverpool game.
The Reds have won three times in Italy at an opponents' ground – winning 2-0 at AS Roma in 2001 and recording 1-0 victories at Inter Milan in 2008 and Udinese in 2012.
If Rhys Williams partners Joe Gomez, it will be the 36th different centre-back combination used under Klopp from the start of a game.
The Reds have played 402 European fixtures, compared to Atalanta's 46.
Atalanta are averaging almost three goals per game this season – 23 in eight matches. In that period they have conceded 15.