With Alisson Becker missing out as a precaution due to a tight leg muscle, the 22-year-old goalkeeper is handed his first European appearance for the Reds between the posts.
Elsewhere, Jordan Henderson returns in midfield, while Joel Matip is back in defence.
Sadio Mane and Curtis Jones are also restored to the XI as Jürgen Klopp makes five changes from the draw at Brighton & Hove Albion at the weekend.
Liverpool: Kelleher, N. Williams, Matip, Fabinho, Robertson, Henderson, Wijnaldum, Jones, Mane, Salah, Jota.
Subs: Adrian, Jaros, Firmino, Minamino, Tsimikas, Origi, R. Williams, Cain, Clarkson.