The centre-back has recovered from the back issue that kept him out of the midweek victory over Tottenham Hotspur.
Elsewhere, Takumi Minamino and Naby Keita come into the starting line-up as Jürgen Klopp makes three changes at Selhurst Park.
Liverpool: Alisson, Alexander-Arnold, Matip, Fabinho, Robertson, Henderson, Wijnaldum, Keita, Minamino, Mane, Firmino.
Subs: Adrian, Kelleher, Salah, Oxlade-Chamberlain, Jones, Origi, R. Williams, Phillips, N. Williams.