The Reds head to Old Trafford on Sunday, a week on from the sides playing out a goalless Premier League draw at Anfield.
Questioned by reporters on what will be the biggest factors in determining his starting XI, Klopp replied: "Opposition and competition.
"We want to win the game, it's clear. It's a cup game, the game will be decided that night and we want to win the game. That's it. That's how we will make the line-up."