The forward will reach the milestone if he features against Sheffield United at Bramall Lane.
Mane’s first 149 top-flight games for the Reds saw him score 70 goals and register 23 assists.
For more pre-match facts and figures from LFC statistician Ged Rea, read on…
Liverpool and Sheffield United have met nine times in the Premier League, with the Reds winning five and drawing two of those fixtures
Victory in this clash would see Liverpool record five consecutive league wins over the Blades for the first time
Each of the Reds’ last eight goals versus Sheffield United have been scored by different players, with only Robbie Fowler (three goals) having scored more than once against the Yorkshire club in the Premier League era
Mohamed Salah has netted in three away games in a row, scoring four times during that sequence
Andy Robertson has started each of Liverpool’s last 29 Premier League matches and is the only Reds player to start every top-flight game this season
Georginio Wijnaldum has featured in the last 47 Premier League games, while Roberto Firmino has not missed a top-flight fixture since May 2019 (an uninterrupted run of 63 matches)