The centre-back is named in the Reds’ starting XI for the first time for a competitive fixture since November 2020 after recovering from knee surgery.
Gomez is one of four changes Jürgen Klopp makes from the weekend win at Leeds United, with Jordan Henderson, Naby Keita and Divock Origi also coming into the line-up.
Virgil van Dijk, Thiago Alcantara and Sadio Mane are on the bench, while Harvey Elliott is ruled out due to the ankle injury sustained at Elland Road.
Liverpool: Alisson, Alexander-Arnold, Matip, Gomez, Robertson, Fabinho, Henderson, Keita, Jota, Salah, Origi.
Subs: Adrian, Kelleher, Van Dijk, Konate, Thiago, Milner, Mane, Oxlade-Chamberlain, Jones, Minamino, Tsimikas, Phillips.