The Portugal forward is restored to the starting line-up as the Reds make two changes from the weekend victory over Aston Villa.
With Fabinho and Virgil van Dijk ruled out after registering suspected positive COVID-19 tests, Ibrahima Konate also comes into the XI, while Roberto Firmino returns on the bench.
Liverpool: Alisson, Alexander-Arnold, Matip, Konate, Robertson, Oxlade-Chamberlain, Thiago, Henderson, Mane, Salah, Jota.
Subs: Kelleher, Pitaluga, Milner, Keita, Firmino, Gomez, Minamino, Tsimikas, Williams.