The forward comes into the XI at Anfield as Jürgen Klopp elects to make alterations following the midweek win over Internazionale at San Siro.
Elsewhere, Joe Gomez, Joel Matip and Kostas Tsimikas come into defence, while Jordan Henderson, Naby Keita and Alex Oxlade-Chamberlain make up the midfield.
Diogo Jota is absent due to an ankle problem, while Roberto Firmino is ruled out with a muscle injury that is being assessed.
Liverpool: Alisson, Gomez, Matip, Van Dijk, Tsimikas, Henderson, Keita, Oxlade-Chamberlain, Mane, Diaz, Salah.
Subs: Kelleher, Fabinho, Konate, Thiago, Milner, Minamino, Robertson, Origi, Elliott.