The Uruguayan is among the substitutes after returning from World Cup duty earlier this week.
Alex Oxlade-Chamberlain comes in for Fabio Carvalho in the only alteration made the XI deployed against Olympique Lyonnais on Sunday.
Liverpool: Kelleher, Milner, Matip, Gomez, Robertson, Bajcetic, Thiago, Elliott, Oxlade-Chamberlain, Salah, Firmino.
Subs: Adrian, Davies, Keita, Tsimikas, Nunez, Carvalho, Clark, Phillips, Doak, Cain, Quansah, Corness, Chambers, Frauendorf.
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