Diogo Jota is in line to make his 100th Reds appearance in all competitions.
Roberto Firmino, meanwhile, could play his 250th league game for the club.
The No.9 has played more times against Bournemouth – 12 – than any other Liverpool player in history.
Victory on the south coast would see Jürgen Klopp record 600 league points as Liverpool manager, becoming the sixth Reds boss to achieve the milestone following Tom Watson, Bill Shankly, Bob Paisley, Kenny Dalglish and Rafael Benitez.
Liverpool’s next top-flight win on the road will be their 250th away from home in the Premier League.
If Mohamed Salah nets he will become the Reds’ leading scorer away from home in the Premier League. He is currently on 55, alongside Michael Owen.
The Egyptian has scored eight goals in his previous seven appearances against Bournemouth.
Klopp’s side have kept five consecutive league clean sheets and six in the last seven top-flight matches.
The current run of 469 minutes without conceding a league goal is the fourth-longest of Klopp’s reign.
In the reverse fixture in August, Liverpool equalled their joint-second-biggest league win ever by defeating the Cherries 9-0, their biggest league victory since 1989 (9-0 versus Crystal Palace).
The Reds have won on their last three league visits to Bournemouth, by scores of 4-0, 4-0 and 3-0.
They are aiming to complete a fifth league double over their opponents in the six seasons the teams have met.
Andy Robertson will celebrate his 29th birthday on the day of the game.
Gary O’Neil, who was appointed Bournemouth boss on a permanent basis in November after taking caretaker charge from August, previously had a spell as assistant coach for Liverpool’s U23s during 2020-21.