The Reds travel to Stamford Bridge for an 8pm BST kick-off – and here are 10 facts and figures about the contest in the capital…
Liverpool are unbeaten in their last four league visits to Stamford Bridge (two wins and two draws) since a defeat in May 2018, and have lost just two of the last 12 encounters at Chelsea, winning six.
That represents the club’s longest unbeaten league run at Chelsea since December 1989 (also four games). Never in their history have they gone five.
The Reds are two goals short of scoring 100 at Chelsea in all competitions.
Jürgen Klopp’s men have scored twice on each of their last three Premier League trips to Stamford Bridge.
The teams drew 0-0 at Anfield back in January, which was a fifth successive match where they could not be separated in normal time.
They met four times in league and cup last season and each finished level after 90 minutes or extra-time. Liverpool went on to win both the Carabao Cup and Emirates FA Cup final showdowns on penalties.
Jordan Henderson could make his 350th appearance in the league for the Reds. He will be the 22nd player to reach the landmark for the club.
James Milner has made 46 career appearances against Chelsea so far – more than any other team. His only goal versus the Blues came in December 2002 for Leeds United.
Harvey Elliott’s 20th birthday falls on the day of this game.
In the Premier League era Liverpool have won 23 of the 61 meetings, while Chelsea have been victorious 21 times and there have been 17 draws.