Liverpool captain Henderson played just under an hour of Monday night’s Euro 2024 qualifier at Old Trafford and he unselfishly teed up Marcus Rashford to put the Three Lions 3-0 up on the stroke of half-time.
Alexander-Arnold, meanwhile, was again deployed in central midfield for the full 90 minutes and provided a sublime pass for Bukayo Saka - who duly lashed in an unstoppable half-volley as part of his hat-trick - in the second half.
Also in European Championship qualifying, Ibrahima Konate and Kostas Tsimikas came up against each other as France defeated Greece 1-0 thanks to a Kylian Mbappe penalty. The Reds duo both completed the entire match in Paris.
Elsewhere, Caoimhin Kelleher was an unused substitute as the Republic of Ireland beat Gibraltar 3-0 in Dublin, while Alexis Mac Allister remained on the bench throughout Argentina’s 2-0 friendly success over Indonesia.