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The Belgian is joined by Mohamed Salah and Roberto Firmino in a three-man forward line, while Philippe Coutinho operates from a deeper role in midfield.
Liverpool: Karius, Alexander-Arnold, Matip, Lovren, Milner, Wijnaldum, Lallana, Coutinho, Salah, Firmino, Origi.
Subs: Mignolet, Gomez, Henderson, Sturridge, Grujic, Klavan, Moreno, Solanke, Flanagan, Kent, Woodburn.