Kick-off is at 2pm GMT and the official matchday programme will keep you informed and entertained with all the latest Reds news.
The special issue pays tribute to Reds defender Satara Murray who will play her final game for the club before returning America after four years with Liverpool.
As well as a chat with the popular defender, the programme is packed full of interviews.
We hear from full-back Leighanne Robe as she prepares to come up against her former club and catch up with her fellow defenders Leandra Little and Jemma Purfield.
Forward Ashley Hodson also talks us through her return to action after almost a year out through injury and how she marked it with a stunning goal.
Manager Vicky Jepson offers her thoughts going into the last 16 cup clash and skipper Sophie Bradley-Auckland gives us the lowdown from inside the dressing-room in her regular captain's column.
There is the lowdown on our visitors from the capital as well as all the latest match action, facts and statistics.
With all this and much more, make sure you pick up your copy of the official matchday programme which will be on sale inside the ground, priced at £2.
Season ticket holders for Liverpool FC and Tranmere Rovers, as well as LFC Members, can gain free entrance to the fixture.