The behind-closed-doors match at Prenton Park kicks off at 2pm BST and will be streamed free on LFCTV GO and YouTube, Twitter and Facebook.
Subscribers can also watch the game live on LFCTV.
The 2pm kick-off time was agreed to tie in with the afternoon league games on the weekends both before and after the contest.
Wednesday’s clash is the Reds' opening Continental Cup fixture in a group that also includes Manchester City and Everton.
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