Trent Alexander-Arnold, Alex Oxlade-Chamberlain, Andy Robertson, Mohamed Salah and Virgil van Dijk return to the starting XI at Old Trafford.
Georginio Wijnaldum is back on the bench after illness.
Liverpool team: Karius, Alexander-Arnold, Lovren, Van Dijk, Robertson, Milner, Can, Oxlade-Chamberlain, Mane, Salah, Firmino.
Substitutes: Mignolet, Wijnaldum, Gomez, Henderson, Lallana, Solanke, Matip.