Can Reina make it six in 11?
We've put together a load of facts you might not have known about Liverpool versus Stoke City...
Last season the teams met four times with Liverpool winning twice, Stoke once and one draw.
Pepe Reina has kept five clean sheets in his 10 games against City.
The Reds have never lost to Stoke at Anfield in the top flight. They have won 39 and drawn 10 of the 49 games.
The Reds' biggest home win against the Potters came in January 1902 when they won 7-0.
Liverpool have scored in 32 of their last 35 home clashes with City in league and cup.
Luis Suarez will aim to become the first Liverpool player to score hat-tricks in successive league games since Ian Rush achieved the feat in November 1982. Rushie famously scored four at Goodison and followed it up with three at home to Coventry the following week.
Last season Stoke scored 11 league goals away from home - the lowest in the top flight.
They also scored fewer Premier League goals in total during the last campaign - 36.
City have yet to finish in the top half of the Premier League - they have finished 12th, 11th, 13th and last season 14th.
Peter Crouch made his Stoke debut against Liverpool in September 2011. He was the Potters' leading scorer last season with 10 league goals.
Stoke have won on this ground three times. They all came in a four-year period in the 1950s in Division Two.
Stoke have gained only three points in the last 27 visits to Anfield. All of them were 0-0 draws - Boxing Day 1970, September 2008 and last January.
They have scored one goal in the last 11 league visits to Anfield. That came from Paul Bracewell in a 5-1 defeat in March 1983.
Stoke's last league clean sheet away from home came at Anfield last January.
They recorded their first win in 12 league games last weekend against Swansea.
Crouch has scored five goals in his last five games in all competitions.
Referee Lee Mason was the man in charge the last time Stoke won away from home in the league, at Blackburn back in January.
Scorers this season (league in brackets):
Liverpool: Suarez 7 (5), Gerrard 3 (2), Sahin 3 (1), Shelvey 3 (0), Borini 1 (0), Coates 1 (0), Downing 1 (0), Johnson 1 (0), Skrtel 1 (1), Wisdom 1 (0), own goals 2 (0).
Stoke: Crouch 5 (4), Walters 2 (1), Jones 1 (0), Kightly 1 (1).